Eda Cakir

Phone: +49 421 200 3535
Mail: ecakir (at) constructor.university
Position: Ph.D. Student (Research Associate)

CV

Eda completed her bachelor’s degree in industrial engineering at METU and worked in strategic positions in various industries for several years. While pursuing her master’s degree in Data Engineering at Jacobs University, she worked at Roche Diagnostics, where she developed tools for the statistical analysis for the comparison of assay measurements and investigated statistical models for degradation rate calculation and shelf-life estimation. In 2021, she started her Ph.D. in computational systems biology.

Research

Eda is currently participating in two projects: (1) a research project funded by the Federal Office for Radiation Protection (BfS) and (2) a joint research project with the Otto von Guericke University Magdeburg, in which she analyzes transcriptome and/or methylation profiles of human /mouse cell cultures. Her research areas include genotype-phenotype relationships, disease networks, network medicine, and synthetic data generators.

Recent Publications

5G-exposed human skin cells do not respond with altered gene expression and methylation profiles
Jyoti Jyoti , Isabel Gronau , Eda Cakir , Marc-Thorsten Hütt , Alexander Lerchl , Vivian Meyer
PNAS Nexus, 2025.
Cite

Cite

                    @article{10.1093/pnasnexus/pgaf127,
 abstract = {Due to the ever-increasing wirelessly transmitted data, the development of new transmission standards and higher frequencies in the 5G band is required. Despite basic biophysical considerations that argue against health effects, there is public concern about this technology. Because the skin penetration depth at these frequencies is only 1 mm or less, we exposed fibroblasts and keratinocytes to electromagnetic fields up to ten times the permissible limits, for 2 and 48 h in a fully blinded experimental design. Sham-exposed cells served as negative, and UV-exposed cells as positive controls. Differences in gene expression and methylation due to exposure were small and not higher than expected by chance. These data strongly support the assessment that there is no evidence for exposure-induced damage to human skin cells.},
 author = {Jyoti, Jyoti and Gronau, Isabel and Cakir, Eda and Hütt, Marc-Thorsten and Lerchl, Alexander and Meyer, Vivian},
 doi = {10.1093/pnasnexus/pgaf127},
 eprint = {https://academic.oup.com/pnasnexus/article-pdf/4/5/pgaf127/63049291/pgaf127.pdf},
 issn = {2752-6542},
 journal = {PNAS Nexus},
 month = {05},
 number = {5},
 pages = {pgaf127},
 title = {5G-exposed human skin cells do not respond with altered gene expression and methylation profiles},
 url = {https://doi.org/10.1093/pnasnexus/pgaf127},
 volume = {4},
 year = {2025}
}

                
The economy of chromosomal distances in bacterial gene regulation
Eda Cakir , Annick Lesne , Marc-Thorsten Hütt
NPJ systems biology and applications, 2021.
Cite

Cite

                    @article{cakir2021economy,
 author = {Cakir, Eda and Lesne, Annick and Hütt, Marc-Thorsten},
 journal = {NPJ systems biology and applications},
 number = {1},
 pages = {1--9},
 publisher = {Nature Publishing Group},
 title = {The economy of chromosomal distances in bacterial gene regulation},
 volume = {7},
 year = {2021}
}